This is group of diseases (AIH – autoimmune hepatitis, PBC – primary biliary cholangitis and PSC – primary sclerosing cholangitis) in which the immune system of an individual attacks its own liver and leads to chronic liver damage. Patients usually present with abnormal liver function tests, jaundice, itching of skin or abdominal pain. Diagnosis is usually made on a liver biopsy although often the disease is initially suspected by doing special immune markers on the blood. The disease is more common in females. Autoimmune hepatitis is one of the commonest cause of liver disease in children